How to use Kloxxado® (naloxone HCl) nasal spray 8 mg
Be ready. Save a life from opioid overdose
With Kloxxado® nasal spray, anyone can reverse an opioid overdose, possibly with just one dose.1
Once administered, it works in the brain, right at the opioid receptor, with front-line power to reverse the deadly effects of the opioid causing the overdose.1,2
How to administer Kloxxado® nasal spray
When a life-threatening opioid overdose happens, administer Kloxxado® – it’s just four simple steps. Then call 911. Kloxxado® nasal spray is not a substitute for emergency medical care.1
Remember:
- If you’re experiencing an overdose, you can’t give Kloxxado® nasal spray to yourself. Make sure those around you know about Kloxxado® and where it’s stored, in case of an emergency.1
- Kloxxado® is ready to use. Do not prime or test the device.1
- Stay with the person after giving Kloxxado® to help them feel more comfortable until emergency help arrives.1
- Overdoses involving highly potent opioids may require more naloxone to reverse.3
- Kloxxado® contains more naloxone per dose.1,4
- Some opioids may outlast the reversal effect of Kloxxado®, so the person may require additional dose(s).1
How to store Kloxxado® nasal spray1
- Keep Kloxxado® nasal spray in the blister and cartons provided until ready to use.
- Store at room temperature 60°F to 77°F (20°C to 25°C).
- Protect from light.
- Do not freeze. Do not expose to temperatures below 41°F (5°C) or above 104°F (40°C).
- Replace Kloxxado® nasal spray before the expiration date on the box.
Keep Kloxxado® nasal spray and all medicines out of the reach of children.
For more information, see complete prescribing information.
References
- KLOXXADO® (naloxone HCl) Nasal Spray [prescribing information]. Columbus, OH: Hikma Specialty USA Inc., 2021
- FDA 2019, “Having Naloxone on Hand Can Save a Life During an Opioid Overdose,” https://www.fda.gov/consumers/consumer-updates/having-naloxone-hand-can-save-life-during-opioid-overdose, Accessed May 3, 2021.
- CDC 2021, “Fentanyl,” https://www.cdc.gov/opioids/basics/fentanyl.html, Accessed May 3, 2021.
- NARCAN® (naloxone HCl) Nasal Spray [prescribing information]. Plymouth Meeting, PA: Emergent BioSolutions Inc., 2020.