How to use Kloxxado® (naloxone HCl) nasal spray 8 mg

Be ready. Save a life from opioid overdose

With Kloxxado® nasal spray, anyone can reverse an opioid overdose, possibly with just one dose.1

Once administered, it works in the brain, right at the opioid receptor, with front-line power to reverse the deadly effects of the opioid causing the overdose.1,2

How to administer Kloxxado® nasal spray

When a life-threatening opioid overdose happens, administer Kloxxado® – it’s just four simple steps. Then call 911. Kloxxado® nasal spray is not a substitute for emergency medical care.1

REMOVE

REMOVE Kloxxado® nasal spray from the box. Peel off the back tab with the triangle (p) to open the KloxxadoTM nasal spray blister.

HOLD

HOLD it with your thumb on the bottom and your first and middle fingers on either side of the nozzle.

INSERT

INSERT the tip of the nozzle into one nostril until your fingers are against the bottom of the person’s nose.

PRESS

PRESS the plunger firmly to give the dose of Kloxxado® nasal spray.

Remember:

  • If you’re experiencing an overdose, you can’t give Kloxxado® nasal spray to yourself. Make sure those around you know about Kloxxado® and where it’s stored, in case of an emergency.1
  • Kloxxado® is ready to use. Do not prime or test the device.1
  • Stay with the person after giving Kloxxado® to help them feel more comfortable until emergency help arrives.1
  • Overdoses involving highly potent opioids may require more naloxone to reverse.3
  • Kloxxado® contains more naloxone per dose.1,4
  • Some opioids may outlast the reversal effect of Kloxxado®, so the person may require additional dose(s).1

How to store Kloxxado® nasal spray1

  • Keep Kloxxado® nasal spray in the blister and cartons provided until ready to use.
  • Store at room temperature 60°F to 77°F (20°C to 25°C).
  • Protect from light.
  • Do not freeze. Do not expose to temperatures below 41°F (5°C) or above 104°F (40°C).
  • Replace Kloxxado® nasal spray before the expiration date on the box.

Keep Kloxxado® nasal spray and all medicines out of the reach of children.

For more information, see complete prescribing information.

Kloxxado® Quick Use Instructions

How to identify an opioid overdose, administer Kloxxado® nasal spray and stay safe until emergency help arrives.

Download

How to get Kloxxado®

Getting Kloxxado® is simple with a prescription from your doctor. You can also save with the Kloxxado® Savings Card.

See How

References

  1. KLOXXADO® (naloxone HCl) Nasal Spray [prescribing information]. Columbus, OH: Hikma Specialty USA Inc., 2021
  2. FDA 2019, “Having Naloxone on Hand Can Save a Life During an Opioid Overdose,” https://www.fda.gov/consumers/consumer-updates/having-naloxone-hand-can-save-life-during-opioid-overdose, Accessed May 3, 2021.
  3. CDC 2021, “Fentanyl,” https://www.cdc.gov/opioids/basics/fentanyl.html, Accessed May 3, 2021.
  4. NARCAN® (naloxone HCl) Nasal Spray [prescribing information]. Plymouth Meeting, PA: Emergent BioSolutions Inc., 2020.