Kloxxado® (naloxone HCl) nasal spray 8 mg2024-03-22T11:56:01-04:00

When the Clock is Ticking,
Choose Kloxxado®

Kloxxado® (naloxone HCl) Nasal Spray 8 mg is more naloxone than Narcan® (naloxone HCl) Nasal Spray 4 mg.1,2

78% of opioid overdose reversals use at least 8 mg of naloxone4

Be ready with Kloxxado® (naloxone HCl) Nasal Spray 8 mg

  • Double the naloxone in one device. 2x as much naloxone as Narcan® Nasal Spray1,2
  • Easy to use. No injection or specialized training required1
  • Can counter fentanyl. 8 mg naloxone to fight stronger opiates1,3
  • Savings card available. Eligible patients may pay as little as $0*

Why higher-dose naloxone?

Based on real-world experiences, this short video explains why 4mg naloxone nasal spray is often not enough to reverse an opioid overdose.4


  1. KLOXXADO® (naloxone HCl) Nasal Spray [prescribing information]. Columbus, OH: Hikma Specialty USA Inc., 2021
  2. NARCAN® (naloxone HCl) Nasal Spray [prescribing information]. Plymouth Meeting, PA: Emergent BioSolutions Inc., 2020
  3. NIDA 2021, “Naloxone DrugFacts,” National Institute on Drug Abuse, https://www.drugabuse.gov/publications/drugfacts/naloxone. Accessed Nov. 17, 2022.
  4. Abdelal et al., 2022, “Real-world study of multiple naloxone administration for opioid overdose reversal among bystanders,” Harm Reduction Journal, 19:49
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Important Safety Information About KLOXXADO® (naloxone HCl) Nasal Spray 8 mg