Naloxone can reverse the effects of opioid overdose1
Naloxone — the medicine in Kloxxado® — plays a vital role in the fight against opioid overdose. It’s been the main antidote to opioid overdoses for more than 50 years.1
Naloxone can counteract the life-threatening effects of an opioid overdose, allowing an overdose victim to regain the ability to breathe normally again.2
The medication only works if a person has opioids in their system and has no effect if opioids are not present.1 So administering naloxone isn’t likely to harm someone, but it could save their life.2
What is Naloxone?
This short video from the Substance Abuse and Mental Health Services Administration (SAMHSA) explains how naloxone works in the body.
Keep Kloxxado® as part of your first aid kit
Just like a car crash or house fire, you’ll never see it coming. But you can do one simple thing to prevent an accidental opioid overdose from being fatal. Keep yourself, your family and your friends prepared.2 Keep Kloxxado® (naloxone HCl) nasal spray nearby as part of your first aid kit.3
78% of opioid overdose reversals involve at least 8 mg of naloxone.6
Kloxxado® vs Narcan®
During an opioid overdose, every minute matters.* Kloxxado® contains twice as much naloxone per dose.†‡
*Non-Fatal Opioid Overdose and Associated Health Outcomes: Final Summary Report. ASPE website. Available at: https://aspe.hhs.gov/sites/default/files/migrated_legacy_files//190846/Nonfatal.pdf. Accessed June 25, 2023.
†KLOXXADO® (naloxone HCl) Nasal Spray [prescribing information]. Columbus, OH: Hikma Specialty USA Inc., 2021.
‡NARCAN® (naloxone HCl) Nasal Spray [prescribing information]. Plymouth Meeting, PA: Emergent BioSolutions Inc., 2020.
The Opioid Epidemic
With the spread of illegally-made, synthetic opioids like fentanyl, overdose deaths have grown across ages, races, ethnicities and communities.*†
*Drug Overdose Deaths Among Persons Aged 10-19 Years - United States, July 2019-December 2021.
†Drug Overdose Deaths Rise, Disparities Widen. Centers for Disease Control and Prevention website. Available at: https://www.cdc.gov/vitalsigns/overdose-death-disparities/index.html. Accessed June 25, 2023.
Facts About Fentanyl
Extremely potent, illegally-made synthetic opioids such as fentanyl and carfentanil are the most common drugs involved in overdose deaths in the United States.*
* Fentanyl Facts. Centers for Disease Control and Prevention website. Available at: https://www.cdc.gov/stopoverdose/fentanyl/index.html. Accessed March 21, 2023.
Kloxxado® Patient Brochure
Read about the key benefits of Kloxxado® nasal spray.
References
- Jordan, M.R. and Morrisonponce, D. 2021, “Naloxone,” StatPearls Publishing, https://pubmed.ncbi.nlm.nih.gov/28722939/, Accessed May 3, 2021.
- FDA 2019, “Having Naloxone on Hand Can Save a Life During an Opioid Overdose,” https://www.fda.gov/consumers/consumer-updates/having-naloxone-hand-can-save-life-during-opioid-overdose, Accessed May 3, 2021.
- KLOXXADO® (naloxone HCl) Nasal Spray [prescribing information]. Columbus, OH: Hikma Specialty USA Inc., 2021
- FDA 2021, “Information about Naloxone,” https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/information-about-naloxone, Accessed June 1, 2021.
- NARCAN® (naloxone HCl) Nasal Spray [prescribing information]. Plymouth Meeting, PA: Emergent BioSolutions, 2020
- Abdelal R, Banerjee A, Carlberg-Racich S, Darwaza N, Ito D, Shoaff J, Epstein J. Real-World Study of Multiple Naloxone Administration for Opioid Overdose Reversal Among Bystanders. JMCP. 2021;27(10-a):S54.
*Maximum value of $40 per box. The Kloxxado® Savings card is not Health Insurance. See complete eligibility and restrictions.